BME

Biochemical & Metabolic Engineering Laboratory

Amity Institute of Biotechnology · Noida, India

Led by Dr. Vivek Kumar Gaur

Central carbon metabolism · hover a metabolite for its enzymes and cofactors

The Lab · Amity Institute of Biotechnology

A metabolic engineering group that starts at the model and ends at the bioreactor.

Most laboratories are good at one half of this. We are built to close the loop: constraint-based models and machine learning propose the intervention, molecular biology builds the strain, and staged fermentation tells us the titre, rate and yield that actually matter to a process engineer.

Our central question is a carbon-accounting one. Every gram of substrate a cell consumes is split between biomass, maintenance and product. Classical strain engineering pushes on that split and hits a wall, because the cell needs to grow. So we build growth-decoupled production systems, and we pick pathways that pay for themselves.

The second half of the lab points outward, at what industrial civilisation has already released. Microplastics, polyaromatic hydrocarbons, pesticide residues and landfill leachate are all, from a microbial point of view, unusual carbon sources — which makes them an engineering problem rather than only a regulatory one.

Design

Genome-scale reconstructions and flux analysis identify which reactions to knock out, up-regulate or import.

Build

Recombinant DNA technology and synthetic control circuits that respond to the state of the culture.

Test

Batch, fed-batch and gas-fed fermentation with online monitoring, and analytics for titre and purity.

Learn

Data-efficient machine learning closes the cycle so the next round of design starts smarter.

Principal Investigator

Dr. Vivek Kumar Gaur

Assistant Professor at the Amity Institute of Biotechnology and convener of SBB-2026. Works on metabolic engineering, synthetic biology and microbial biosurfactants.

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Research Programmes · 6 active lines

Six lines of work, one carbon ledger.

Select a programme to see what it covers and the papers behind it.

Publications

The record.

Graphical abstracts as published, with the paper underneath. Search, filter, and follow any entry through to the journal.

Projects · Current work

What we are building, and who it is for.

Four programmes currently occupy most of the lab's time. Strain, route and process design stay in the lab until they are published.

Global Network · — countries

The lab is not just a room. It is the entire world.

Co-authoring groups on the papers above, and the institutions the lab brought to Noida for SBB-2026. Drag to spin the globe, tap it to unfold the world flat, then click any tinted country to zoom into it.

Region

SBB-2026 · Convened by this lab

An international conference, run out of the lab.

Three days, four tracks, invited speakers from twenty-odd countries — the whole programme in one deck.

Hybrid · Amity University Uttar Pradesh, Noida

International Conference on Sustainable Biotechnology and Bio-innovations

“Sustainable Biotechnology and Bioinnovations for a Circular Bioeconomy”

Dates: 25–27 Feb 2026
Convener: Dr. V. K. Gaur
Invited speakers: —
Session chairs: 22

Co-conveners Prof. Sumedha Mohan and Dr. Amit Kumar Chaurasia; conference chairs Prof. Pooja Vijayaraghavan and Prof. Rachana Singh; international chair Prof. Sunghoon Park (UNIST, South Korea).

Conference site ↗

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